• Dr. Nicole Vumbaco | DVM

Recheck #1: Summary of Discussion Points

Updated: May 12

*Disclaimer: Notes outlined below are unique to my case and disease profile. I have shared an edited summary of my Doctor's discussion and approach to assist others in learning about Bartonellosis. However, this should absolutely not be used for self-treatment. Please consult your doctor*

5.8.2020 (2 months into Phase 1):

  • Began discussing my joint pain, tears, boney changes and soft tissue injuries. All part of Connective Tissue Component of Bartonellosis

  • MRI-went over all recent MRI's (C-spine, T-spine, Lumbar Spine, Brain and bilateral hip findings)- stenosis at C5-C6 (right shoulder pain left arm numbness, possibly related); Spondyloarthropathy and facet arthropathy: ligamentum laxity caused the bridging/spondylosis and boney changes along the spine- body's attempt to stabilize. Bilateral leg numbness and pain, lumbar changes vs disease pathophys. Treatment should resolve joint pain as hypermobility improves; if any hot spots left post treatment (PrP, Novacaine, etc)- no invasive procedures are recommended at this stage.

  • Bartonella can take years on poly-ABX therapy and long-term Herbals- As previously discussed, treatment of Bartonellosis requires at least two intracellular antibiotics. Fantastic study published looking at 2 drug regiments for bartonella. Single meds do not work. This is a multifaceted disease that needs a multimodal approach...had a patient as bad as my case and is now able to work 12 hours without pain. Do not stress about the joint degeneration and tears that have happened. Decline all invasive procedures until disease is better controlled. This will get better.

  • Joint replacements in patients with Vector Borne Disease, and surgery typically goes very wrong and should be avoided during treatment or at all if possible.

  • What is an Ozone Joint Injection? Novacaine first- Resets cell membrane to resting potential. If resting potential is low, it is easily upset/over responsive. Ozone sets the membrane potential higher, so body is less responsive to any stimuli. Ozone reacts with lipids and proteins. Sets off a cascade of signals to upregulate anti-inflammatory enzymes and materials. Hyper-oxygenate the area, reacts within milliseconds, creating an oxygen rich environment which is great for healing

  • PrP Injection: will help with regeneration of tissues and cartilage. Recommends waiting on joint injections. Patients with tick borne infections don’t respond well to this intervention until the bacteria burden is lower, can discuss in a year or two. Can absolutely make things worse. Any inflammation, good or bad, is what bartonella wants and where it infiltrates

  • EKG had normal QT interval (important), intermittent VPCs. Continue Coq10.

  • Considering Methylene Blue: recent study showed surprise effect on Bartonella but they are unable to find labs to test levels-MIC s very low- Unsure what therapeutic range is but shown to kill bartonella in both lag and stationary phase, can help with bladder symptoms, sometimes used in interstitial cystitis. Dr. JB sent paper. My Urologist, Dr. W 100 percent approved as well. Used in Urogesic for Interstitial Cystitis. Can help with relief there and shows good coverage for intracellular disease. Used to treat Malaria and Babesia. ON the surprise list of meds that work well with bartonella. Downside, it is expensive. Lacking ability to measure blood levels of MB and how it translates to in-body availability. Bladder irritability will come down as bacterial load comes down.

  • Phase 2: Clarithromycin/Bioxin: Excellent for Lyme and Bartonella. Good addition to the Bactrim. Powerful cytochrome inhibitor. Inhibits that enzyme and with rifampin on board, that combo pushes pedal to the medal for penetration. 500 mg tablets. Start low and slow. I do not get to add in this drug or any other until I am at a final Bactrim dose that my body tolerates. Never add in new antimicrobrials while herxing. START ½ pill q24 hours, see what happens. Sh